Don-A Tablet, 1 Strip [Domperidone 10 mg]

Don-A Tablet, 1 Strip [Domperidone 10 mg]


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  • 14pcs tablets/strip
  • Indicated for: Acute nausea and vomiting, Stimulation of gut motility, Functional dyspepsia.

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Dosage and Administration

DON-A (Domperidone) should be taken 15-30 minutes before a meal. The usual recommended oral dose is as follows:

Tablet/ Suspension/ Paediatric drops:

Adult: 10 mg – 20 mg (1 – 2 DON-A tablet or 10 – 20 ml DON-A suspension) every 4 – 8 hours.

Elderly: Same as for adults.

Children: 0.2 – 0.4 body weight (2 – 4 ml suspension or 0.4 – 0.8 ml Paediatric drops/ 10 kg body weight) every 4 – 8 hours.

By rectum in suppositories:

Adults (including elderly): 30 – 60 mg every 4 – 8 hours.

Children: The maximum daily dose rectally in children’s is 30 mg for those weighting 10 to 25 kg. Dose may be divided throughout day if necessary.Maximum period of treatment is 12 weeks.

Side Effects

Extrapyramidal reactions are seen in 0.05% of patients in clinical studies. Domperidone may produce hyperprolactinemia (1.3%). This may result in galactorrhea, breast enlargement, soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), skin rash and itch (0.1%) may all follow treatment with Domperidone.


Domperidone is contraindicated to patients having known hypersensitivity to this drug and in case of neonates. Domperidone should not be used when gastrointestinal stimulation might be dangerous i.e. gastrointestinal haemorrhage, obstruction, perforation or immediately after surgery.


Domperidone should be used with absolute caution in case of children because there may be an increased risk of extrapyramidal reactions in young children because of an incompletely developed blood brain barrier.

The safety of Domperidone has not been proven and it is, therefore, not recommended during pregnancy. Animal studies have not demonstrated teratogenic effect on the fetus. Domperidone may precipitate galactorrhea and improve postnatal lactation. It is secreted in breast milk.


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